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NEW RESEARCH SUPPORTS GLYMPHATIC INVOLVEMENT IN ME/CFS
A paper published in International Journal of Molecular Sciences on 27 November 2025 explores “Glymphatic System Dysregulation as a Key Contributor to ME/CFS” – something Dr Perrin first proposed over 35 years ago!
We believe the ME/CFS medical / scientific community will be interested in seriously considering glymphatic dysfunction an important contributor to its pathophysiology. If so, therapeutics that modulate glymphatic function may also benefit patients with ME/CFS.
– Int. J. Mol. Sci. 2025, 26(23), 11524;
https://doi.org/10.3390/ijms262311524
While the paper does not reference Dr Perrin’s pioneering work, it is another strong sign that the wider scientific community is continuing to validate the fundamentals of the Perrin Technique™.
Osteo Talk: Podcast Episode with Perrin Technique Practitioners
In celebration of the upcoming Australian Perrin Technique workshops, we’re revisiting this wonderful Osteo Talk podcast from Osteopathy Australia:
“Practice and Potential: The Perrin Technique’s Role in Clinical Care and Careers.”
In this episode, licensed Perrin Technique Practitioners Dr. Amanda Oosterweghel and Dr. Ray Power share how their practices have evolved to meet the growing demand for care among patients with ME/CFS and long COVID.
They discuss:
How the Perrin Technique has transformed their approach to osteopathic care
The real difference it’s making for patients’ lives
Why this work continues to inspire both practitioners and patients alike
Amanda also shares a particularly moving patient story – one that brought tears to the eyes of Dr. Raymond Perrin himself when he heard it.
A huge thank you to Osteopathy Australia, Amanda, and Ray for highlighting both the practical and human side of the Perrin Technique by sharing their insights and experiences on the podcast.
Listen to the full episode here: Osteo Talk: The Perrin Technique’s role in clinical care and careers
PERRIN TECHNIQUE WORKSHOP – UTAH, USA
We are thrilled to share the success of our very first Perrin Technique workshop in Utah!
Hosted at Myotherapy Massage College in Salt Lake City from January 30th to February 1st, this workshop would not have been possible without the dedication of Perrin Technique Practitioner Rachel Tobler! Rachel was instrumental in bringing this event to Utah and played a crucial role in ensuring its success.
A warm welcome to all those who joined us for the workshop:
Alissa Hyde
Allyson Gilmore
Alyse Aguirre
Analee Hallman
Angela Parsons
Cameron Smith
Cristine Pena
Debbie Rinquest
Deborah McGraw
Edward Rangel
Heather Wilde
Holly DiFrancesco
Ivonne Saldana
Kanina E Garner
Kristian Hansen
Lesha Nelson
Linda Birch
Matthew Tobler
Rebecca B. Cope
Stephanie Forsberg
Suzanne Dunbar
Taber Cope
The workshop was an enormous success, bringing together a knowledgeable and experienced group of practitioners eager to expand the reach of the Perrin Technique across the USA – we are thrilled to welcome new Perrin Technique Practitioners in Utah, Texas, Florida, Minnesota, and Wyoming!
We’d like to express a huge thank you to Rachel and Matthew Tobler, who were wonderful hosts in welcoming Dr. Perrin to Utah!
THROUGH THE LOOKING GLASS: A TRIUMPH IN PRINT AND PRACTICE
The Academy of Nutritional Medicine (AONM) featured a glowing review of Dr. Ray Perrin’s latest book, Through the Looking Glass: Diagnosing and Treating Long COVID Using the Perrin Technique, in their November newsletter. Described as a “tour-de-force”, the review shares how the book combines cutting-edge research with over three decades of clinical practice, offering invaluable insights for both patients and practitioners. To download the review in full, click the following link:
The AONM review praises the “impressive updated explanation” of how the Perrin Technique works, building on Ray’s groundbreaking 2020 Medical Hypotheses article, which linked disturbances in the neuro-lymphatic drainage to Long COVID and ME/CFS. The review also highlights how the book explores the role of the subarachnoid lymphatic-like membrane (SLYM), describing the publication as both timely and comprehensive.
Interest in Dr. Perrin’s work has surged following coverage in The Telegraph and other media. Since its release on 7th November, Through the Looking Glass sold out within one week due to overwhelming demand, with limited stock now remaining of Dr. Perrin’s other books too (The Perrin Technique: Second Edition and Concise Perrin Technique Handbook)
Perrin Technique™ featured in The Telegraph
An article published online in The Telegraph spotlights Dr. Raymond Perrin’s work and the development of the Perrin Technique for ME/CFS and long COVID.
It explores the origins of the technique, discusses the recent major breakthroughs in science which back up the foundations of the Perrin Technique and includes insights from the latest book, Through the Looking Glass.
Prof. Adrian Heald, consultant physician at Salford Royal (part of Northern Care Alliance NHS Foundation Trust), adds valuable support from a recognised NHS perspective as he calls for more research into the Perrin Technique and notes the technique’s “positive results” for ME/CFS and long COVID patients:
“We’re increasingly learning about the physiology on which the Perrin Technique is based. The science is slowly catching up with what Dr. Perrin has been proposing as a technique for many years… Anecdotally we have seen positive results in patients with very difficult to treat chronic fatigue/ME who have been seeing Dr Perrin.”
– Professor Adrian Heald, consultant physician at Salford Royal (part of Northern Care Alliance NHS Foundation Trust)
The full article is available here via The Telegraph’s website (subscription required, with a free month’s trial available)
Following its global online publication in November which sparked significant interest, Dr. Perrin’s interview with The Telegraph was also featured in print on 11th January in the UK. This fantastic feature continues to shine a spotlight on the Perrin Technique, helping to spread awareness worldwide.
PERRIN TECHNIQUE FEATURED ON LONG COVID PODCAST
We are thrilled to announce that Dr. Perrin recently featured on the Long Covid Podcast, in a two-part series!
Part 1: Breakthroughs in the Lymphatic System
In the first episode, Ray discusses the intricate connections between the sympathetic nervous system and chronic conditions like Long COVID and ME/CFS and emphasises the importance of understanding the body’s drainage systems to promote healing and recovery. Key topics include:
- The discovery of the lymphatic system and its implications.
- The connection between Long COVID, ME/CFS, and toxic buildup in the brain.
- Overview of treatment methodologies and their effectiveness.
Listen to Part 1 here: Long Covid Podcast – Dr Raymond Perrin (Part One)
Part 2: Pathways to Recovery
In the second episode, Dr. Perrin explores how the Perrin Technique can help alleviate symptoms and support long-term recovery. He shares compelling case studies and clinical insights, covering topics such as:
- Diagnostic methods for identifying Long COVID symptoms.
- The role of heavy metals and toxicity in illness.
- Self-massage and breathing exercises.
Listen to Part 2 here: Long Covid Podcast – Dr Raymond Perrin (Part Two)
PERRIN TECHNIQUE WORKSHOP – CALIFORNIA, USA
Our first Perrin Technique workshop of 2025, held from 24th – 26th January, saw a change in venue due to the devastating wildfires in Beverly Hills. We’re incredibly grateful to newly licensed Perrin Technique Practitioner Belinda McDonald for stepping in at the last minute to host us at her fantastic clinic Signature Physical Therapy in San Clemente.
It was a hugely successful workshop, bringing together a very knowledgable, experienced group of practitioners – it was a delight to welcome them to the Perrin Technique class:
Aaron Orpelli
Belinda McDonald
Cindy Roberts
Colleen Jamieson
Crystal Bennett
Daphne Mosko
Deborah Crawford
Gary Strauss
Gina Anderson
Kanpiwat ‘MJ’ Himacharoen
Kimby Maxson
Laine Miller
Lori Relph
Megan Barragatto
Nancy Lopez
Rana Rand
Susan Jeffries
Tina Shin
Tracy Griffiths
A huge heartfelt thank you goes to Melinda Bassett and Perrin Technique Practitioner Leslyn Keith for their tireless efforts in organising the workshop, and to Perrin Technique Practitioner Kristine King, who is undertaking the Advanced Course 2025-2026, for assisting Dr. Perrin over the weekend.
Dr. Perrin alongside Perrin Technique Practitioners Michelle Sanderson and Kristine King
We were delighted to welcome back Perrin Technique Practitioner Michelle Sanderson to the three-day workshop, attending for the second time to stay on top of the latest research and updates from Dr. Perrin—a testament to her commitment to the Perrin Technique!
As part of Dr. Perrin’s commitment to supporting the community, a portion of the workshop funds was donated to the wildfire relief efforts in the Beverly Hills area.
STUDY CONFIRMS BRAINS WASTE-CLEARANCE PATHWAYS IN HUMANS
A groundbreaking study from Oregon Health & Science University (OHSU) has, for the first time, confirmed the existence of a functioning glymphatic system in living humans — a theory central to the Perrin Technique!
Researchers recruited five volunteers undergoing neurosurgery between 2020-2023. During the procedure, the volunteers received an injection of a dye (gadolinium) into their cerebrospinal fluid, followed by MRI scans to trace the dye’s movement through the brain. The results, published on October 7, 2024, in the Proceedings of the National Academy of Sciences (PNAS), show cerebrospinal fluid flowing through perivascular spaces, detailing a waste-clearance network in the brain
This mapping of pathways that clear neurotoxins to the body’s lymphatic and venous systems offers powerful validation for Dr. Perrin’s approach to treating ME/CFS, Fibromyalgia, long COVID, and other conditions.
LONG COVID BOOK: OUT NEXT WEEK!
The wait is almost over! ‘Through the Looking Glass: Diagnosing and Treating Long COVID Using The Perrin Technique’ hits the shelves next Thursday, November 7!
Through the Looking Glass takes readers through what long COVID is and how the symptoms can be reversed using lymphatic drainage of the brain. For a first look, our publisher Hammersmith Health Books is offering a preview of the first chapter on their website:
Sneak Preview: Read First Chapter Online Here
In this practical handbook, Dr. Perrin spells out the basics of ‘why’ and ‘how’ to use the Perrin Technique to underpin recovery from long COVID and restore healthy lymphatic drainage from the brain following COVID-19 infection or vaccination. He brings together what is now known about the virus and its long-term consequences with his research and clinical experience of more than 30 years to offer solutions that can restore health, as the many case histories included in the book illustrate.
The foreword is written by Dr. Yassine Bendiabdallah, a Functional Medicine Specialist, who shares how he discovered the Perrin Technique during his own journey with long COVID, finding it to be a “comprehensive, evidence-based approach” that transformed his recovery. He now considers it an indispensable part of his therapeutic toolkit for treating post-viral conditions.
This highly anticipated book is currently available for pre-order across many major online booksellers worldwide!